Holden (Affleck) and best friend Banky (Lee), New Jersey comic book artists, attend a convention in New York where Holden is immediately attracted to fellow artist Alyssa (Adams). His ego is quickly deflated when Alyssa lets him know she's a lesbian. They try for friendship, head into a rocky romance, and then Holden discovers Alyssa's had a wild (and heterosexual) past, which pushes all his emotional buttons. Writer/director Smith supplies his trademark sharp dialogue, and the leads all contribute fine performances. Jay (Mewes) and Silent Bob (Smith), from Smith's earlier pics, make another appearance and supply the story that gives the film its title.